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Table 5 Odds ratios (ORs) and 95% confidence intervals (CIs) for atherosclerosis in relation to platelets by status of HTLV-1 infection among non-hypertensive subjects

From: Possible mechanisms underlying the association between human T-cell leukemia virus type 1 (HTLV-1) and hypertension in elderly Japanese population

 

Platelet tertiles

p

1 SD increment of platelets

T1 (low)

T2 (moderate)

T3 (high)

HTLV-1 infection (−)

 No. of participants

299

266

242

  

 No. of cases (%)

80 (26.8)

79 (29.7)

64 (26.4)

  

 Model 1 (2 categories)

1.00

1.09 (0.76, 1.57)

0.633

1.12 (0.94, 1.34)

 Model 1 (3 categories)

1.00

1.33 (0.90, 1.98)

1.26 (0.83, 1.90)

0.253

 Model 2 (2 categories)

1.00

0.97 (0.66, 1.42)

0.615

1.06 (0.88, 1.28)

 Model 2 (3 categories)

1.00

1.27 (0.85, 1.91)

1.11 (0.71, 1.71)

0.878

HTLV-1 infection (+)

 No. of participants

73

68

71

  

 No. of cases (%)

20 (27.4)

20 (29.4)

32 (45.1)

  

 Model 1 (2 categories)

1.00

2.36 (1.26, 4.44)

0.008

1.39 (1.04, 1.85)

 Model 1 (3 categories)

1.00

1.15 (0.54, 2.46)

2.54 (1.21, 5.31)

0.008

 Model 2 (2 categories)

1.00

2.63 (1.31, 5.29)

0.007

1.44 (1.05, 1.97)

 Model 2 (3 categories)

1.00

1.21 (0.55, 2.65)

2.88 (1.30, 6.40)

0.011

  1. Model 1 adjusted only for sex and age, Model 2 adjusted further for sex and age, body mass index, triglycerides, HDL-cholesterol, HbA1C, white blood cell, and γ-GTP. Platelet tertiles: For men < 19.3 × 104/μL for T1 (low), 19.3–23.3 × 104/μL for T2 (moderate), ≥ 23.4 × 104/μL for T3 (high). For women < 20.7 × 104/μL for T1 (low), 20.7–24.8 × 104/μL for T2 (moderate), ≥ 24.9 × 104/μL for T3 (high). The 1 standard deviation (SD) increment of platelet was 5.24 × 104/μL both for men and women
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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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