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Table 1 Summary of the studies used in the systematic review and meta-analysis

From: Anemia as a risk factor for tuberculosis: a systematic review and meta-analysis

Author/year

Study design

Country

Sample size

OR/HR (95% CI)

Source of population

Age of participant

Anemia severity

Lienhardt et al./2005# [27]

Case-control

West Africa

1,166

3.50* (2.57–4.79)

Community

Adult

Mild

Lienhardt et al./2005# [27]

Case-control

West Africa

10.80* (6.80–17.20)

Community

Adult

Moderate and severe

Taha et al./2011# [28]

Case-control

Ethiopia

809

1.87 (1.576–2.17)

HIV +

Adult

Mild

Taha et al./2011# [28]

Case-control

Ethiopia

4.35 (3.97–4.72)

HIV +

Adult

Moderate and severe

Kerkhoff et al./2014## [11]

Cross-sectional

S.Africa

485

2.05* (1.48–2.62)

HIV +

Adult

Mild

Kerkhoff et al./2014## [11]

Cross-sectional

S.Africa

3.65* (3.16–4.12)

HIV +

Adult

Moderate

Kerkhoff et al./2014## [11]

Cross-sectional

S.Africa

6.91* (6.05–7.78)

HIV +

Adult

Severe

Pefura et al./2013 [29]

Cross-sectional

Cameroon

857

1.60 (1.03–2.50)

PTB +

Adult

Not defined

Iroezindu et al./2016 [24]

Cross-sectional

Nigeria

339

4.50 (0.60–31.70)

HIV +

Adult

Not defined

Beshir et al./2019 [10]

Cohort

Ethiopia

428

7.04 (1.03–48.15)

HIV +

Children

Not defined

Ayalaw et al./2015 [30]

Cohort

Ethiopia

271

2.23 (1.19–4.15)

HIV +

Children

Not defined

Batista et al./2013[31] 

Cohort

Brazil

1,596

2.93 (1.86–4.62)

HIV +

Adult

Not defined

Chu et al./2019 [17]

Cohort

Taiwan

109,501

1.99 (1.77–2.25)

Community

Adult

Not defined

Alemu et al./2016 [22]

Cohort

Ethiopia

645

2.70 (1.60–4.50)

HIV +

Children

Not defined

McDermid et al./2013 [32]

Cohort

Gambia

1,139

1.14 ** (1.02–1.27)

HIV +

Adult

Not defined

Li et al./2013 [33]

Cohort

Tanzania

5,040

1.40** (1.00–1.90)

HIV +

Children

Not defined

Enju et al./2015## [21]

Cohort

Tanzania

67,686

1.22 (1.13–1.33)

HIV +

Adult

Mild

Enju et al./2015## [21]

Cohort

Tanzania

1.66 (1.55–1.79)

HIV +

Adult

Moderate

Enju et al./2015## [21]

Cohort

Tanzania

2.03 (1.86–2.22)

HIV +

Adult

Severe

Kerkhoff et al./2015## [20]

Cohort

S.Africa

1,521

0.96*(0.72–1.63)

HIV+

Adult

Mild

Kerkhoff et al./2015## [20]

Cohort

S.Africa

1.27*(0.99–1.62)

HIV+

Adult

Moderate

Kerkhoff et al./2015## [20]

Cohort

S.Africa

1.22*(0.94–1.58)

HIV+

Adult

Severe

Phyo et al./2019## [23]

Cohort

Myanmar

7,859

2.10 (1.70–2.80)

HIV+

Adult

Mild

Phyo et al./2019## [23]

Cohort

Myanmar

4.30 (3.40–5.40)

HIV+

Adult

Moderate

Phyo et al./2019## [23]

Cohort

Myanmar

4.90 (3.30–7.20)

HIV+

Adult

Severe

Chang et al./2015## [34]

Cohort

Nigeria

12,996

2.48* (2.02–3.03)

HIV+

Adult

Mild and moderate

Chang et al./2015## [34]

Cohort

Nigeria

4.36*(1.98–9.62)

HIV+

Adult

Severe

Choun et al./2013## [35]

Cohort

Cambodia

2,956

2.10 (1.40–3.30)

HIV+

Adult

Mild and moderate

Choun et al./2013## [35]

Cohort

Cambodia

3.40 (2.10–5.50)

HIV+

Adult

Severe

  1. NB * crude odds ratio for cross-sectional and case-control studies, and crude hazard ratio for cohort studies, **adjusted risk ratio and those without * or ** are adjusted odd ratio for cross-sectional and case-control studies, and adjusted hazard ratio for cohort studies, # the data split into two, ## the data split into three; HIV+ human immunodeficiency virus positive patients; HR hazard ratio; RR relative risk; OR odds ratio; PTB pulmonary—tuberculosis patient; S. Africa South Africa