Optimization and validation of a highly sensitive method for determining glyphosate in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: a methodological study

Table 3 Absolute and relative matrix factors of 10 individuals

Sample ID	Creatinine (g/L)	Absolute matrix factors (row data of peak area)		Relative matrix factors (with IS collection)
Sample ID	Creatinine (g/L)	Tenfold dilution	CreMDi_0.05	Tenfold dilution	CreMDi_0.05
1	1.28	0.57	0.69	1.10	0.90
2	0.48	1.02	0.75	1.02	0.92
3	0.32	0.95	0.79	1.18	1.07
4	1.13	0.60	0.83	0.95	1.03
5	0.45	1.76	0.90	1.51	1.10
6	1.62	0.51	0.72	1.34	0.92
7	0.79	0.84	0.77	1.97	1.10
8	0.21	1.12	0.83	1.03	1.21
9	0.69	0.49	0.72	1.57	1.02
10	1.37	0.82	0.52	1.34	0.80
%RSD		41.9	12.9	22.9	11.4

CreMDi_0.05 creatinine-matching dilution to concentration at 0.05 g/L, RSD relative standard deviation

ISSN: 1347-4715