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Table 5 Sex-specific odds ratios (OR) and 95% confidence intervals (CIs) for advanced periodontitis in relation to human T cell leukemia virus-1 (HTLV-1) infections by status of atherosclerosis

From: Association between human T cell leukemia virus type-1 (HTLV-1) infection and advanced periodontitis in relation to atherosclerosis among elderly Japanese: a cross-sectional study

 

Atherosclerosis

Interaction

(−)

(+)

HTLV-1 infection

p

HTLV-1 infection

p

p

(−)

(+)

(−)

(+)

Men

 No. of subjects

186

31

 

111

25

  

 No. of case (%)

45 (24.2)

7 (22.6)

 

29 (26.1)

12 (48.0)

  

 Model 1

1.00

0.88 (0.35, 2.18)

0.774

1.00

2.68 (1.09, 6.96)

0.032

0.106

 Model 2

1.00

0.79 (0.30, 2.05)

0.624

1.00

3.39 (1.24, 9.24)

0.017

0.071

 Model 3

1.00

0.81 (0.31, 2.11)

0.662

1.00

3.76 (1.34, 10.56)

0.012

0.058

Women

 No of subjects

326

69

 

121

38

  

 No of case (%)

63 (19.3)

8 (11.6)

 

23 (19.0)

10 (26.3)

  

 Model 1

1.00

0.51 (0.23, 1.14)

0.100

1.00

1.56 (0.66, 3.70)

0.309

0.083

 Model 2

1.00

0.51 (0.23, 1.16)

0.108

1.00

1.46 (0.57, 3.69)

0.430

0.111

 Model 3

1.00

0.50 (0.22, 1.15)

0.102

1.00

1.48 (0.58, 3.76)

0.413

0.090

  1. Advanced periodontitis is defined as periodontal pocket ≥ 6.0 mm. Atherosclerosis is defined as carotid intima-media thickness (CIMT) ≥ 1.1 mm. Model 1: adjusted only for age. Model 2: adjusted further for smoking status (never, former, current), number of remaining teeth, status of decayed teeth (presence, absence), body mass index (BMI), HDL cholesterol, triglycerides, hemoglobin A1c (HbA1c), reticulocyte count, and CIMT. Model 3: adjusted further for antihyperlipidemic medication use (yes, no) and glucose-lowering medication use (yes, no)