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Table 4 Odds ratios (OR) and 95% confidence intervals (CI) for reduced maximum voluntary tongue pressure against the palate (MTP) in relation to rs3782886 genotype

From: Impact of single nucleotide polymorphism on short stature and reduced tongue pressure among community-dwelling elderly Japanese participants: a cross-sectional study

 

rs3782886

p for trend

Minor allele frequencies

 

Non-minor homo

Minor homo

  
 

Major homo (A/A)

Hetero (A/G)

(G/G)

  

Total participants

 No. at risk

326

187

24

  

 No. of cases (percentage)

112 (34.4)

54 (28.9)

14 (58.3)

  

 Model 1

1.00

0.72 (0.48, 1.09)

2.66 (1.10, 6.42)

0.805

1.04 (0.76, 1.43)

1.00

2.97 (1.25, 7.09)

0.014

 

 Model 2

1.00

0.76 (0.49, 1.17)

2.92 (1.17, 7.29)

0.566

1.11 (0.79, 1.55)

1.00

3.26 (1.33, 8.03)

0.010

 

Women

 No. at risk

209

105

18

  

 No. of cases (percentage)

65 (31.1)

35 (33.3)

11 (61.1)

  

 Model 1

1.00

1.12 (0.67, 1.87)

3.37 (1.21, 9.42)

0.067

1.44 (0.98, 2.12)

1.00

3.25 (1.18, 8.93)

0.022

 

 Model 2

1.00

1.14 (0.66, 1.95)

3.18 (1.07, 9.43)

0.088

1.43 (0.95, 2.15)

1.00

3.04 (1.04, 8.85)

0.042

 
  1. Model 1: adjusted only for sex and age. Model 2: further adjusted for body mass index, systolic blood pressure, alcohol consumption (never drinker, former drinker, current drinker [<23, 23–45, 46–68, and ≥69 g/week]), smoking status (never smoker, former smoker, current smoker), history of stroke, HDL-cholesterol, triglycerides, HbA1C, and serum creatinine. Reduced maximum voluntary tongue pressure against the palate is defined as the lowest tertile of the study population (<26.5 kPa for men and <24.1 kPa for women)